Sartorius Stedim Biotech presents a new small-scale crossflow device

1 min read
Ideal for process development applications: SSB’s new small-scale and single-use filter device Sartocon Slice 50.
Ideal for process development applications: SSB’s new small-scale and single-use filter device Sartocon Slice 50.

Sartocon Slice 50 is offered as an encapsulated and ready-to-use crossflow module with a filter area of 50 cm2 and a wide variety of molecular weight cutoffs. The cGMP validated self-contained unit eliminates the need for a compression holder and is available in a choice of two polymers: The Hydrosart® membrane is a stable polymer suitable for a broad pH range and can be depyrogenated using NaOH at elevated temperatures. It is extremely hydrophilic, making it non-protein-binding and virtually non-fouling, and delivers an exceptional high flux. The polyethersulfone membrane (PESU), which is well established in the biotechnological and pharmaceutical industries, is a stable polymer that is ideal for a broad pH and temperature range.

Sartorius says a major benefit of the crossflow filter device is its linear scalability, along with identical materials of construction. This eases transfer of process development results to the next scale up level.

Sartocon Slice 50 can easily be interfaced with SSB’s recently launched SARTOFLOW® Smart benchtop crossflow system, as well as with many other laboratory-scale filtration systems.