“We designed this instrument specifically for labs needing to maintain their current GC or single quadrupole GC-MS workflows while adding triple quadrupole capabilities with minimal disruption,” said Paul Silcock, marketing manager, GC-MS for Thermo Fisher Scientific. “The TSQ Duo system allows users to run their current methods and then easily move over to MS/MS analysis when the time is right for them, on a familiar system using the Thermo Scientific Dionex Chromeleon Chromatography Data System (CDS).”
The Chromeleon CDS’ new selected ion monitoring (SIM) bridge software capability can help simplify the adoption of MS/MS methods on the TSQ Duo.
The new TSQ Duo system is based on the Thermo Scientific TRACE 1300 gas chromatograph and TSQ mass spectrometer platform, and is designed to perform both single and triple quadrupole analysis on the same instrument. In single quadrupole mode, the TSQ Duo system can deliver full-scan spectra, searchable against popular MS libraries, and SIM quantitation. In triple quadrupole mode, selected reaction monitoring (SRM) can improve sensitivity by allowing clean detection, even in complex matrices.
“This is the first time that chromatographers have been able to access the power of triple quadrupole mass spectrometry using the Chromeleon CDS,” said Frank Tontala, Chromeleon CDS product manager for Thermo Fisher Scientific.