New system delivers purified water for pharmaceuticals

1 min read

Unlike other similar systems, which are custom designed for each application, Nexus from Veolia Water Solutions & Technologies is made up of one standard, packaged, pre-validated distribution system.

The system is designed to deliver purified water and water for injection for flow rates up to 30m3/h (132 US gpm), and each package incorporates a booster pump, 316L stainless steel pipe work (ASME BPE as optional), double tube sheet heat exchanger and control panel. The hygienic design and fabrication in 316L stainless steel are compliant with GAMP, International Society for Pharmaceutical Engineering (ISPE), current good manufacturing practice (cGMP) and US Food and Drug Administration (FDA) requirements. Nexus comes with conductivity monitoring, temperature control and loop flow meter, with options for TOC and ozone monitoring.

The system can be sanitised either using electrolytically-generated ozone with UV ozone destruction, or hot water at 85°C/185°F (121°C/249°F for WFI). Both sanitisation solutions are suitable within the pharmaceutical industry.

The unit is supplied with a full standardised validation pack, including functional design specification, design qualification, installation qualification and factory acceptance test documentation. It is skid-mounted, helping reduce lead times and speed up installation and start-up.