Toray develops high-efficiency membrane for biopharma that doubles filtration performance

Toray Industries Inc has developed a high-efficiency separation membrane module for biopharmaceutical manufacturing processes that delivers more than double the filtration performance of conventional counterparts by reducing clogging.

Biopharmaceutical manufacturing
Biopharmaceutical manufacturing - Image © hapsuwanArt - stock.adobe.com.

The module should also increase biopharmaceutical yields to more than 90% and enhance purification.

The company will initially supply prototypes to diverse customers to evaluate in purification processes for producing gene therapy drugs with a view to swift commercialization.

Toray’s new separation membrane module comprises a depth filter incorporating multiple types of non-woven fabric and a hollow fiber ultrafiltration membrane.

The company employed technologies it amassed in innovating air filter products to develop the depth filter. Optimizing the fiber thickness and void structure of the nonwoven fabric has enhanced filtration, improving gene therapy permeability and impurity removal.

In creating its ultrafiltration membrane, Toray employed hollow fiber membranes incorporating anti-fouling, surface-hydrophilization technology that it developed through its work on artificial kidneys. This advance prevents substances from adhering to the membrane, resisting protein adsorption and reducing clogging.

Toray is looking to launch sales during the fiscal year ending March 2026.