Porvair Sciences' Microlute CP is a new generation of Solid Phase Extraction (SPE) 96-well microplates and cartridges that take SPE which aim to enhance the reproduction of analyte extraction and recovery from biological, environmental and chemical samples. Unlike traditional loose-packed SPE methods, Microlute CP uses a hybrid structure, a solid interconnected network of evenly distributed pores combined with the retentive media. This design aims to enhance the flow-through of samples to maximise interactions between analytes and the solid phase to improve the reproducible SPE method in performance, cleanliness and sensitivity. Microlute CP microplates and cartridges benefit from a recent technological development which enables immobilisation of active media within the structure of Vyon, a porous plastic to form a structured interconnected network of even distributed pores. This hybrid technology results in the formation of a chemically active porous filter, a unique structure that overcomes inconsistencies and variabilities often associated with loose-packed methods.
The porous properties of Microlute CP allows for consistent and controlled flow of samples throughout the filter leading to overall better extraction and recovery performance. Meanwhile, the single solid structure used in Microlute CP plates eliminates the need for multiple porous filters for media support which can further disrupt flow rates and lead to unwanted material breakthrough.