Hypersil GOLD HILIC from Thermo Fisher Scientific is available with 1.9, 3 and 5 µm particle sizes. HILIC works by incorporating water in the highly organic mobile phase to form, an adsorbed water-rich layer on the polar stationary phase surface into which analyte molecules partition. Retention is governed by dipole-dipole interactions and hydrogen bonding mechanisms. Furthermore, the highly organic mobile phase contains low salt levels, making Hypersil GOLD HILIC columns ideal for use with electrospray mass spectroscopy.

Hypersil GOLD HILIC columns are designed for applications within drug discovery, food testing and environmental analysis.