The new crossflow filter device is designed for use in biotechnological applications, especially for membrane screening and small-volume process development.
Sartocon Slice 50 is an encapsulated, ready-to-use crossflow module with a filter area of 50 cm2 and a wide variety of molecular weight cutoffs. The self-contained unit eliminates the need for a compression holder and is available in a choice of two polymers. The first is the Hydrosart membrane, which is a stable polymer suitable for a broad pH range and can be depyrogenated using NaOH at elevated temperatures. It is extremely hydrophilic, making it non-protein-binding and virtually non-fouling. The second is a polyethersulfone membrane (PESU), which is well established in the biotechnological and pharmaceutical industries, which is a stable polymer that is ideal for a broad pH and temperature range.
A major benefit of the new crossflow filter device is its linear scalability, along with identical materials of construction. This eases transfer of process development results to the next scale up level. The Sartocon Slice 50 can easily be used with SSB’s recently launched Sartoflow Smart benchtop crossflow system, as well as with many other laboratory-scale filtration systems.
